LAHEY CLINIC • TUFTS MEDICAL CENTER • TUFTS UNIVERSITY
| Keywords | Technology | Business Opportunity |
| Neurostimulation Neurology | Spinal cord implants LC100 | Improve quality of life for people with complete quadriplegia. Device works by replacing damaged portions of the spinal cord with implantable electrical micro-arrays, allowing the brain to continue communication with the lower extremities. contact: john.cosmopoulos@tufts.edu |
| Tissue engineering Tissue regeneration | Bio-LOM tissue-engineered devices T001327 | Create well-defined, 3D, multilayer scaffolds for tissue engineering that permit enhanced tissue growth and fluid flow. Bio-LOM (biologically relevant, laminated object manufacturing) is a blend of bioengineering, rapid manufacturing, and microfabrication technologies. contact: martin.son@tufts.edu |
| Laboratory research | Transfection device for post-mitotic cells T001364 | Introduce genetic material consistently and reliably into post-mitotic cells—without special reagents or lengthy protocols. This fluid dynamic technology could develop into a bench-top system for automated transfection or a robotic system for high-throughput, automated transfection. contact: john.cosmopoulos@tufts.edu |
| Invasive Neurology | Endovascular cerebral spinal fluid drain 381 | Implantable shunt for draining cerebral spinal fluid. contact: nina.green@tufts.edu |
| Medical training Surgical training | Dynamic, minimally invasive training and testing T001418 | Train medical personnel to perform endoscopic procedures, emphasizing a dynamic simulation environment to enhance the experience. contact: colm.lawler@tufts.edu |
| Sensors Life sciences Multiple applications Technology platform | Silk optic–based devices/ sensors T001430 | Create devices and sensor systems that are optically addressable, biocompatible, disposable, degradable, and consumable. Life sciences applications include implantable diagnostic devices, medical multifunctional sensors, and biocompatible lap-on-chip approaches. contact: martin.son@tufts.edu |
| Invasive Healthcare informa-tion technology | Ultra low–power biomedical implants T001440 | Reduce power consumption in circuits used to transfer data wirelessly from biomedical implants. Enable wireless power telemetry for reliable implant operation over a patient’s lifetime—without the need for replacement. contact: martin.son@tufts.edu |
| Invasive Endoscopy | Fiber optic shape tracking T001490 | Measure and continuously track the shape and position of an object whose shape changes dynamically with time (such as an endoscope). contact: colm.lawler@tufts.edu |
| Oral health Therapeutic | Treatment for gingival recession T001547 | New treatment for gingival recession—with significant clinical data—supports development of a commercial, disposable product for use by the attending dentist. contact: john.cosmopoulos@tufts.edu |
| Imaging Research | Confocal light scattering spectroscopic imaging T001551 | Observe back-scattering signals in living cells, with confocal sectioning ability. contact: colm.lawler@tufts.edu |
| Tissue regeneration Tissue repair | Developing vascularised, living skin T001576 | Drug screening, tissue regeneration, wound healing. contact: nina.green@tufts.edu |
| Noninvasive Neurology | Detecting cerebral ischemia 278 | Application of electrical stimuli to different sides of the body and their detection by a machine-readable medium that stores executable instructions for detecting ischemia within the brain of a patient. contact: colm.lawler@tufts.edu |
| Noninvasive Healthcare | Safety skin-suturing device 382 | Novel suturing device for central lines. This device protects the needle at all times to avoid needle stick injuries to care givers. Improves safety and reduces healthcare costs. contact: john.cosmopoulos@tufts.edu |
| Invasive Orthopedic | Arthroscopic cannula 406 | Improved cannula that facilitates access to a joint under surgery and allows enhanced fluid movement. contact: colm.lawler@tufts.edu |
| Imaging Diagnostics | Integrated CMOS microarrays for neuronal/cell imaging T001496 | Obtain simultaneous, high-throughput optical and electrical measurements to enable cell-based assays for medical diagnostics. This complementary metal–oxide–semiconductor (CMOS) technology allows for optically assisted impedance spectroscopy of cells/neurons and living tissues, both in vivo and in vitro. contact: martin.son@tufts.edu |
| Imaging | Electro-optical sensor for peripheral nerves T001400 | Combine two existing instruments (an electrical nerve stimulator and a near-infrared tissue spectrophotometer) into an electro-optical sensor for the study of peripheral nerves. contact: colm.lawler@tufts.edu |

